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A Case for Antifungal Stewardship

Publication ,  Journal Article
Miller, RA
Published in: Current Fungal Infection Reports
March 1, 2018

Purpose of Review: The expanding utilization of limited available antifungal agents has led to a pressing need to implement interventions to ensure appropriate usage. The global emergence of resistant, difficult-to-treat invasive fungal infections among the most vulnerable patient populations is a call to action to develop a multifaceted antifungal stewardship approach. Recent Findings: Candida species demonstrating multi-drug resistance, including highly resistant Candida auris, are emerging threats. Azole-resistant Aspergillus fumigatus, likely initially originating in the environment, likewise presents a treatment challenge. Routine empiric and prophylactic antifungal use, though effective, further complicates this issue, with the emergence of breakthrough mold infections. Early evidence supports success with antifungal stewardship programs. Summary: Broad antifungal stewardship approaches that optimize antifungal drug usage, facilitate provider education, and monitor fungal epidemiology are crucial steps to preserve the antifungal armamentarium. Future development of novel diagnostic and treatment strategies will further facilitate management of invasive fungal infections.

Duke Scholars

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Published In

Current Fungal Infection Reports

DOI

EISSN

1936-377X

ISSN

1936-3761

Publication Date

March 1, 2018

Volume

12

Issue

1

Start / End Page

33 / 43

Related Subject Headings

  • 3207 Medical microbiology
  • 3202 Clinical sciences
 

Citation

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Chicago
ICMJE
MLA
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Miller, R. A. (2018). A Case for Antifungal Stewardship. Current Fungal Infection Reports, 12(1), 33–43. https://doi.org/10.1007/s12281-018-0307-z
Miller, R. A. “A Case for Antifungal Stewardship.” Current Fungal Infection Reports 12, no. 1 (March 1, 2018): 33–43. https://doi.org/10.1007/s12281-018-0307-z.
Miller RA. A Case for Antifungal Stewardship. Current Fungal Infection Reports. 2018 Mar 1;12(1):33–43.
Miller, R. A. “A Case for Antifungal Stewardship.” Current Fungal Infection Reports, vol. 12, no. 1, Mar. 2018, pp. 33–43. Scopus, doi:10.1007/s12281-018-0307-z.
Miller RA. A Case for Antifungal Stewardship. Current Fungal Infection Reports. 2018 Mar 1;12(1):33–43.
Journal cover image

Published In

Current Fungal Infection Reports

DOI

EISSN

1936-377X

ISSN

1936-3761

Publication Date

March 1, 2018

Volume

12

Issue

1

Start / End Page

33 / 43

Related Subject Headings

  • 3207 Medical microbiology
  • 3202 Clinical sciences