Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease.

Journal Article (Journal Article)

A new synthetic oral retinoid, 13-cis retinoic acid, is fairly well tolerated in patients and appears to be effective in those with Darier's disease and lamellar ichthyosis. It is less effective in those with pityriasis rubra pilaris. The mechanism of action of 13-cis retinoic acid in disorders of keratinization is unknown at the present time; however, it does not appear to cause lysosomal proliferation in therapeutic doses.

Full Text

Duke Authors

Cited Authors

  • Gilgor, RS; Chiaramonti, A; Goldsmith, LA; Lazarus, GS

Published Date

  • April 1980

Published In

Volume / Issue

  • 25 / 4

Start / End Page

  • 380 - 385

PubMed ID

  • 6928816

International Standard Serial Number (ISSN)

  • 0011-4162


  • eng

Conference Location

  • United States