Penicillamine-induced pemphigus. Immunoglobulin from this patient induces plasminogen activator synthesis by human epidermal cells in culture: mechanism for acantholysis in pemphigus.

Journal Article (Journal Article)

The incubation of cultured epidermal cells with IgG obtained from a 56-year-old man with penicillamine-induced pemphigus resulted in an increase in extracellular and intracellular plasminogen activator. This suggests that penicillamine-induced pemphigus and spontaneously occurring pemphigus share common pathophysiologic processes in the induction of blister formation.

Full Text

Duke Authors

Cited Authors

  • Hashimoto, K; Singer, K; Lazarus, GS

Published Date

  • June 1984

Published In

Volume / Issue

  • 120 / 6

Start / End Page

  • 762 - 764

PubMed ID

  • 6539102

International Standard Serial Number (ISSN)

  • 0003-987X

Digital Object Identifier (DOI)

  • 10.1001/archderm.120.6.762


  • eng

Conference Location

  • United States