Penicillamine-induced pemphigus. Immunoglobulin from this patient induces plasminogen activator synthesis by human epidermal cells in culture: mechanism for acantholysis in pemphigus.
Journal Article (Journal Article)
The incubation of cultured epidermal cells with IgG obtained from a 56-year-old man with penicillamine-induced pemphigus resulted in an increase in extracellular and intracellular plasminogen activator. This suggests that penicillamine-induced pemphigus and spontaneously occurring pemphigus share common pathophysiologic processes in the induction of blister formation.
Full Text
Duke Authors
Cited Authors
- Hashimoto, K; Singer, K; Lazarus, GS
Published Date
- June 1984
Published In
Volume / Issue
- 120 / 6
Start / End Page
- 762 - 764
PubMed ID
- 6539102
International Standard Serial Number (ISSN)
- 0003-987X
Digital Object Identifier (DOI)
- 10.1001/archderm.120.6.762
Language
- eng
Conference Location
- United States