Epidermolysis bullosa hereditaria letalis: pathology, natural history and therapy.

Journal Article (Journal Article)

A patient with epidermolysis bullosa hereditaria letalis had the characteristic electron microscopic lesions not only in the skin, but also in the gastro-intestinal, genito-urinary and respiratory tracts. Administration of dexamethasone to this patients resulted in a significant decrease in the blistering. Although the patient died, long term survival in this disease is not rare. We report that staining tissue specimens from patients with epidermolysis bullosa with fluorescein-labelled bullous pemphigoid antibody is a reliable method for differentiating between junctional and dystrophic disease.

Full Text

Duke Authors

Cited Authors

  • Schachner, L; Lazarus, GS; Dembitzer, H

Published Date

  • January 1, 1977

Published In

Volume / Issue

  • 96 / 1

Start / End Page

  • 51 - 58

PubMed ID

  • 843437

International Standard Serial Number (ISSN)

  • 0007-0963

Digital Object Identifier (DOI)

  • 10.1111/j.1365-2133.1977.tb05185.x


  • eng

Conference Location

  • England