Metal-Organic Framework as a Protective Coating for Biodiagnostic Chips.

Journal Article (Journal Article)

Zeolitic imidazolate framework-8 (ZIF-8) grown around antibodies anchored to plasmonic nanostructures serves as a protective layer to preserve the biorecognition ability of antibodies stored at room and elevated temperatures for several days. The biofunctionality of the ZIF-8-protected biochip can be restored by a simple water-rinsing step, making it highly convenient for use in point-of-care and resource-limited settings.

Full Text

Duke Authors

Cited Authors

  • Wang, C; Tadepalli, S; Luan, J; Liu, K-K; Morrissey, JJ; Kharasch, ED; Naik, RR; Singamaneni, S

Published Date

  • February 2017

Published In

Volume / Issue

  • 29 / 7

PubMed ID

  • 27925296

Pubmed Central ID

  • PMC5369648

Electronic International Standard Serial Number (EISSN)

  • 1521-4095

Digital Object Identifier (DOI)

  • 10.1002/adma.201604433


  • eng

Conference Location

  • Germany