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Pulmonary Delivery of Therapeutic and Diagnostic Gases.

Publication ,  Journal Article
Zapol, WM; Charles, HC; Martin, AR; Sá, RC; Yu, B; Ichinose, F; MacIntyre, N; Mammarappallil, J; Moon, R; Chen, JZ; Geier, ET; Darquenne, C ...
Published in: J Aerosol Med Pulm Drug Deliv
April 2018

The 21st Congress for the International Society for Aerosols in Medicine included, for the first time, a session on Pulmonary Delivery of Therapeutic and Diagnostic Gases. The rationale for such a session within ISAM is that the pulmonary delivery of gaseous drugs in many cases targets the same therapeutic areas as aerosol drug delivery, and is in many scientific and technical aspects similar to aerosol drug delivery. This article serves as a report on the recent ISAM congress session providing a synopsis of each of the presentations. The topics covered are the conception, testing, and development of the use of nitric oxide to treat pulmonary hypertension; the use of realistic adult nasal replicas to evaluate the performance of pulsed oxygen delivery devices; an overview of several diagnostic gas modalities; and the use of inhaled oxygen as a proton magnetic resonance imaging (MRI) contrast agent for imaging temporal changes in the distribution of specific ventilation during recovery from bronchoconstriction. Themes common to these diverse applications of inhaled gases in medicine are discussed, along with future perspectives on development of therapeutic and diagnostic gases.

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Published In

J Aerosol Med Pulm Drug Deliv

DOI

EISSN

1941-2703

Publication Date

April 2018

Volume

31

Issue

2

Start / End Page

78 / 87

Location

United States

Related Subject Headings

  • Respiratory System
  • Oxygen
  • Nitric Oxide
  • Nebulizers and Vaporizers
  • Magnetic Resonance Imaging
  • Lung
  • Hypertension, Pulmonary
  • Humans
  • Gases
  • Drug Delivery Systems
 

Citation

APA
Chicago
ICMJE
MLA
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Zapol, W. M., Charles, H. C., Martin, A. R., Sá, R. C., Yu, B., Ichinose, F., … Katz, I. (2018). Pulmonary Delivery of Therapeutic and Diagnostic Gases. J Aerosol Med Pulm Drug Deliv, 31(2), 78–87. https://doi.org/10.1089/jamp.2017.1431
Zapol, Warren M., H Cecil Charles, Andrew R. Martin, Rui C. Sá, Binglan Yu, Fumito Ichinose, Neil MacIntyre, et al. “Pulmonary Delivery of Therapeutic and Diagnostic Gases.J Aerosol Med Pulm Drug Deliv 31, no. 2 (April 2018): 78–87. https://doi.org/10.1089/jamp.2017.1431.
Zapol WM, Charles HC, Martin AR, Sá RC, Yu B, Ichinose F, et al. Pulmonary Delivery of Therapeutic and Diagnostic Gases. J Aerosol Med Pulm Drug Deliv. 2018 Apr;31(2):78–87.
Zapol, Warren M., et al. “Pulmonary Delivery of Therapeutic and Diagnostic Gases.J Aerosol Med Pulm Drug Deliv, vol. 31, no. 2, Apr. 2018, pp. 78–87. Pubmed, doi:10.1089/jamp.2017.1431.
Zapol WM, Charles HC, Martin AR, Sá RC, Yu B, Ichinose F, MacIntyre N, Mammarappallil J, Moon R, Chen JZ, Geier ET, Darquenne C, Prisk GK, Katz I. Pulmonary Delivery of Therapeutic and Diagnostic Gases. J Aerosol Med Pulm Drug Deliv. 2018 Apr;31(2):78–87.
Journal cover image

Published In

J Aerosol Med Pulm Drug Deliv

DOI

EISSN

1941-2703

Publication Date

April 2018

Volume

31

Issue

2

Start / End Page

78 / 87

Location

United States

Related Subject Headings

  • Respiratory System
  • Oxygen
  • Nitric Oxide
  • Nebulizers and Vaporizers
  • Magnetic Resonance Imaging
  • Lung
  • Hypertension, Pulmonary
  • Humans
  • Gases
  • Drug Delivery Systems