An update of research evidence on nutrition and prostate cancer.

Published

Journal Article (Review)

BACKGROUND: Prostate cancer (PCa) remains a leading cause of mortality in US and other countries. Preclinical and clinical studies have examined the role of nutrition and dietary intake on the incidence and progression of PCa with mixed results. OBJECTIVE: The objective of this chapter is to provide an update of recent published literature and highlight progress in the field. MAIN FINDINGS: Low carbohydrate intake, soy protein, ω3 fat, green teas, tomatoes and tomato products and the herbal mixture-zyflamend showed promise in reducing PCa risk or progression. On the contrary, a higher animal fat intake and a higher β-carotene status may increase risk. A "U" shape relationship may exist between folate, vitamin C, vitamin D and calcium with PCa risk. Conclusion Despite the inconclusive findings, the potential for a role of dietary intake for the prevention and treatment of PCa remains promising. Maintaining a healthy body weight and following a healthy dietary pattern including antioxidant rich fruits and vegetables, reduced animal fat and refined carbohydrates, should be encouraged. CONCLUSION: Despite the inconclusive findings, the potential for a role of dietary intake for the prevention and treatment of PCa remains promising. Maintaining a healthy body weight and following a healthy dietary pattern including antioxidant rich fruits and vegetables, reduced animal fat and refined carbohydrates, should be encouraged.

Full Text

Duke Authors

Cited Authors

  • Lin, P-H; Aronson, W; Freedland, SJ

Published Date

  • June 2019

Published In

Volume / Issue

  • 37 / 6

Start / End Page

  • 387 - 401

PubMed ID

  • 29103966

Pubmed Central ID

  • 29103966

Electronic International Standard Serial Number (EISSN)

  • 1873-2496

Digital Object Identifier (DOI)

  • 10.1016/j.urolonc.2017.10.006

Language

  • eng

Conference Location

  • United States