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High mortality rates for very low birth weight infants in developing countries despite training.

Publication ,  Journal Article
Carlo, WA; Goudar, SS; Jehan, I; Chomba, E; Tshefu, A; Garces, A; Parida, S; Althabe, F; McClure, EM; Derman, RJ; Goldenberg, RL; Bose, C ...
Published in: Pediatrics
November 2010

OBJECTIVE: The goal was to determine the effect of training in newborn care and resuscitation on 7-day (early) neonatal mortality rates for very low birth weight (VLBW) infants. The study was designed to test the hypothesis that these training programs would reduce neonatal mortality rates for VLBW infants. METHODS: Local instructors trained birth attendants from 96 rural communities in 6 developing countries in protocol and data collection, the World Health Organization Essential Newborn Care (ENC) course, and a modified version of the American Academy of Pediatrics Neonatal Resuscitation Program (NRP), by using a train-the-trainer model. To test the impact of ENC training, data on infants of 500 to 1499 g were collected by using a before/after, active baseline, controlled study design. A cluster-randomized, controlled trial design was used to test the impact of the NRP. RESULTS: A total of 1096 VLBW (500-1499 g) infants were enrolled, and 98.5% of live-born infants were monitored to 7 days. All-cause, 7-day neonatal mortality, stillbirth, and perinatal mortality rates were not affected by ENC or NRP training. CONCLUSIONS: Neither ENC nor NRP training of birth attendants decreased 7-day neonatal, stillbirth, or perinatal mortality rates for VLBW infants born at home or at first-level facilities. Encouragement of delivery in a facility where a higher level of care is available may be preferable when delivery of a VLBW infant is expected.

Duke Scholars

Published In

Pediatrics

DOI

EISSN

1098-4275

Publication Date

November 2010

Volume

126

Issue

5

Start / End Page

e1072 / e1080

Location

United States

Related Subject Headings

  • Teaching
  • Survival Rate
  • Stillbirth
  • Resuscitation
  • Pregnancy
  • Pediatrics
  • Neonatology
  • Midwifery
  • Inservice Training
  • Infant, Very Low Birth Weight
 

Citation

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Carlo, W. A., Goudar, S. S., Jehan, I., Chomba, E., Tshefu, A., Garces, A., … First Breath Study Group, . (2010). High mortality rates for very low birth weight infants in developing countries despite training. Pediatrics, 126(5), e1072–e1080. https://doi.org/10.1542/peds.2010-1183
Carlo, Waldemar A., Shivaprasad S. Goudar, Imtiaz Jehan, Elwyn Chomba, Antoinette Tshefu, Ana Garces, Sailajanandan Parida, et al. “High mortality rates for very low birth weight infants in developing countries despite training.Pediatrics 126, no. 5 (November 2010): e1072–80. https://doi.org/10.1542/peds.2010-1183.
Carlo WA, Goudar SS, Jehan I, Chomba E, Tshefu A, Garces A, et al. High mortality rates for very low birth weight infants in developing countries despite training. Pediatrics. 2010 Nov;126(5):e1072–80.
Carlo, Waldemar A., et al. “High mortality rates for very low birth weight infants in developing countries despite training.Pediatrics, vol. 126, no. 5, Nov. 2010, pp. e1072–80. Pubmed, doi:10.1542/peds.2010-1183.
Carlo WA, Goudar SS, Jehan I, Chomba E, Tshefu A, Garces A, Parida S, Althabe F, McClure EM, Derman RJ, Goldenberg RL, Bose C, Hambidge M, Panigrahi P, Buekens P, Chakraborty H, Hartwell TD, Moore J, Wright LL, First Breath Study Group. High mortality rates for very low birth weight infants in developing countries despite training. Pediatrics. 2010 Nov;126(5):e1072–e1080.

Published In

Pediatrics

DOI

EISSN

1098-4275

Publication Date

November 2010

Volume

126

Issue

5

Start / End Page

e1072 / e1080

Location

United States

Related Subject Headings

  • Teaching
  • Survival Rate
  • Stillbirth
  • Resuscitation
  • Pregnancy
  • Pediatrics
  • Neonatology
  • Midwifery
  • Inservice Training
  • Infant, Very Low Birth Weight