The importance of cholesterol medication adherence: the need for behavioral change intervention programs.

Published online

Journal Article

Lipid-lowering medications have been shown to be efficacious, but adherence is suboptimal. This is a narrative, perspective review of recently published literature in the field of medication adherence research for lipid-lowering medications. We provide an overview of the impact of suboptimal adherence and use a World Health Organization framework (patient, condition, therapy, socioeconomic, and health system-related systems) to discuss factors that influence hyperlipidemia treatment adherence. Further, the review involves an evaluation of intervention strategies to increase hyperlipidemia treatment adherence with a special focus on mHealth interventions, patient reminders on packaging labels, nurse- and pharmacist-led interventions, and health teams. It also highlights opportunities for pharmaceutical companies to support and scale such behavioral interventions. Medication adherence remains a challenge for the long-term management of chronic conditions, especially those involving asymptomatic disease such as hyperlipidemia. To engage patients and enhance motivation over time, hyperlipidemia interventions must be targeted to individual patients' needs, with sequencing and frequency of contact tailored to the various stages of behavioral change.

Full Text

Duke Authors

Cited Authors

  • Bosworth, HB; Ngouyombo, B; Liska, J; Zullig, LL; Atlani, C; Beal, AC

Published Date

  • 2018

Published In

Volume / Issue

  • 12 /

Start / End Page

  • 341 - 348

PubMed ID

  • 29563777

Pubmed Central ID

  • 29563777

International Standard Serial Number (ISSN)

  • 1177-889X

Digital Object Identifier (DOI)

  • 10.2147/PPA.S153766


  • eng

Conference Location

  • New Zealand