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Update on Surgical Management of Small Bowel Neuroendocrine Tumors.

Publication ,  Journal Article
Moris, D; Ntanasis-Stathopoulos, I; Tsilimigras, DI; Vagios, S; Karamitros, A; Karaolanis, G; Griniatsos, J; Papalampros, A; Papaconstantinou, I ...
Published in: Anticancer Res
March 2018

The widespread use of endoscopy and imaging in combination with the continuous update of the staging systems for neuroendocrine tumors has led to an increase in the incidence of small intestinal neuroendocrine tumors (si-NENs) globally. Despite high survival rates, severe complications may occur even in early stages due to the anatomic location of the primary site and the desmoplastic reaction. Surgery plays a central role in the management of patients with si-NENs. Excision of locoregional disease along with extensive lymph node dissection should be performed in fit patients, even in the presence of metastases. Multimodality treatment of liver metastases includes hepatectomy, ablative techniques and liver transplantation. Hormone therapy with somatostatine analogs is of high importance for symptomatic control; special caution should be exercised both pre- and intra-operatively. A multidisciplinary approach is essential in order to provide personalized therapeutics for patients with si-NENs. Clinical research and specialization in this field should be further encouraged.

Duke Scholars

Published In

Anticancer Res

DOI

EISSN

1791-7530

Publication Date

March 2018

Volume

38

Issue

3

Start / End Page

1267 / 1278

Location

Greece

Related Subject Headings

  • Precision Medicine
  • Postoperative Complications
  • Oncology & Carcinogenesis
  • Neuroendocrine Tumors
  • Neoplasm Staging
  • Liver Transplantation
  • Liver Neoplasms
  • Intestine, Small
  • Intestinal Neoplasms
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Moris, D., Ntanasis-Stathopoulos, I., Tsilimigras, D. I., Vagios, S., Karamitros, A., Karaolanis, G., … Felekouras, E. (2018). Update on Surgical Management of Small Bowel Neuroendocrine Tumors. Anticancer Res, 38(3), 1267–1278. https://doi.org/10.21873/anticanres.12349
Moris, Demetrios, Ioannis Ntanasis-Stathopoulos, Diamantis I. Tsilimigras, Stylianos Vagios, Andreas Karamitros, Georgios Karaolanis, John Griniatsos, et al. “Update on Surgical Management of Small Bowel Neuroendocrine Tumors.Anticancer Res 38, no. 3 (March 2018): 1267–78. https://doi.org/10.21873/anticanres.12349.
Moris D, Ntanasis-Stathopoulos I, Tsilimigras DI, Vagios S, Karamitros A, Karaolanis G, et al. Update on Surgical Management of Small Bowel Neuroendocrine Tumors. Anticancer Res. 2018 Mar;38(3):1267–78.
Moris, Demetrios, et al. “Update on Surgical Management of Small Bowel Neuroendocrine Tumors.Anticancer Res, vol. 38, no. 3, Mar. 2018, pp. 1267–78. Pubmed, doi:10.21873/anticanres.12349.
Moris D, Ntanasis-Stathopoulos I, Tsilimigras DI, Vagios S, Karamitros A, Karaolanis G, Griniatsos J, Papalampros A, Papaconstantinou I, Glantzounis GK, Spartalis E, Blazer DG, Felekouras E. Update on Surgical Management of Small Bowel Neuroendocrine Tumors. Anticancer Res. 2018 Mar;38(3):1267–1278.

Published In

Anticancer Res

DOI

EISSN

1791-7530

Publication Date

March 2018

Volume

38

Issue

3

Start / End Page

1267 / 1278

Location

Greece

Related Subject Headings

  • Precision Medicine
  • Postoperative Complications
  • Oncology & Carcinogenesis
  • Neuroendocrine Tumors
  • Neoplasm Staging
  • Liver Transplantation
  • Liver Neoplasms
  • Intestine, Small
  • Intestinal Neoplasms
  • Humans