Controversies and Challenges of Ventricular Assist Device Therapy.

Journal Article (Journal Article;Review)

Left ventricular assist device (LVAD) therapy has emerged as an increasingly vital facet of the treatment algorithm for advanced heart failure. Growing experience with LVAD support has led to substantial improvements in outcomes, with 1-year survival rates approaching that of cardiac transplantation. These therapeutic refinements have engendered growing interests in the potential for expanding the clinical indications for LVAD therapy to patients with less advanced heart failure. The primary obstacles to this evolution of care center largely on the prevention and/or management of the adverse events associated with LVAD therapy along with patient preference. Many programs also face the mounting difficulty of balancing quality outcomes with the increased volume of implants. During the recently assembled Users Meeting organized by St. Jude Medical, heart failure clinicians from nearly 50 LVAD implanting centers discussed these and other challenges and controversies impacting the field. The present review summarizes the key insights gleaned from this meeting.

Full Text

Duke Authors

Cited Authors

  • Lima, B; Bansal, A; Abraham, J; Rich, JD; Lee, SS; Soleimani, B; Katz, JN; Kilic, A; Young, JS; Patel, CB; Joseph, SM; Evolving Mechanical Support Research Group (EMERG),

Published Date

  • May 15, 2018

Published In

Volume / Issue

  • 121 / 10

Start / End Page

  • 1219 - 1224

PubMed ID

  • 29576232

Electronic International Standard Serial Number (EISSN)

  • 1879-1913

Digital Object Identifier (DOI)

  • 10.1016/j.amjcard.2018.01.034


  • eng

Conference Location

  • United States