Neutrophil Gelatinase Associated Lipocalin (NGAL) as a Biomarker. Does It Apply in Abdominal Aortic Aneurysms? A Review of Literature


Journal Article (Review)

© 2014, Association of Surgeons of India. Neutrophil gelatinase associated lipocalin (NGAL) as a protein derived from neutrophils has recently been the field of investigation in a wide range of diseases (renal disease, coronary artery disease, etc). The MEDLINE/PubMed database was searched for publications with the medical subject heading “NGAL” and keywords “Abdominal aortic aneurysm (AAA),” “biomarker,” and “growth”. We restricted our search to date. In this review, we included 38 articles and abstracts that were accessible and available in English. An effort to further explain the role of NGAL within AAA has been made. NGAL seems to be a hopeful marker for the pathogenesis and the progression of abdominal aortic aneurysms (AAAs), which has significant morbidity and mortality rates.

Full Text

Duke Authors

Cited Authors

  • Karaolanis, G; Moris, D; Palla, VV; Karanikola, E; Bakoyiannis, C; Georgopoulos, S

Published Date

  • December 1, 2015

Published In

Volume / Issue

  • 77 /

Start / End Page

  • 1313 - 1317

Electronic International Standard Serial Number (EISSN)

  • 0973-9793

International Standard Serial Number (ISSN)

  • 0972-2068

Digital Object Identifier (DOI)

  • 10.1007/s12262-014-1099-1

Citation Source

  • Scopus