Single-center experience of transplantation for polycystic liver disease.


Conference Paper

BACKGROUND: Polycystic liver disease (PLD) may lead to massive hepatomegaly, abdominal distension, pain, and various degrees of dyspnea. The surgical treatment of this entity remains controversial. METHODS: We report our experience from a retrospective analysis of 23 patients suffering from PLD who were treated with liver transplantation (LT) in our institution. RESULTS: Liver transplantation for PLD patients with extensive hepatic involvement offers excellent symptoms relief. The actuarial 1-, 3-, and 5-year survival rate after transplantation was 86%. CONCLUSIONS: Our experience demonstrates that PLD patients with extensive hepatic involvement and who are treated with LT have good long-term prognosis and excellent symptoms relief. LT might be considered in severe PLD cases where conventional surgery is not a curative option, and it must be balanced against the risks of LT and lifelong commitment to immunosuppression.

Full Text

Duke Authors

Cited Authors

  • Vernadakis, S; Moris, D; Mamarelis, G; Fouzas, I; Mathe, Z; Kaiser, G; Paul, A; Sotiropoulos, G

Published Date

  • November 2014

Published In

Volume / Issue

  • 46 / 9

Start / End Page

  • 3209 - 3211

PubMed ID

  • 25420861

Pubmed Central ID

  • 25420861

Electronic International Standard Serial Number (EISSN)

  • 1873-2623

International Standard Serial Number (ISSN)

  • 0041-1345

Digital Object Identifier (DOI)

  • 10.1016/j.transproceed.2014.09.158