Secondary hyperoxaluria: a risk factor for kidney stone formation and renal failure in native kidneys and renal grafts.

Journal Article (Review;Journal Article)

Secondary hyperoxaluria is a multifactorial disease affecting several organs and tissues, among which stand native and transplanted kidneys. Nephrocalcinosis and nephrolithiasis may lead to renal insufficiency. Patients suffering from secondary hyperoxaluria, should be promptly identified and appropriately treated, so that less renal damage occurs. The aim of this review is to underline the causes of hyperoxaluria and the related pathophysiologic mechanisms, which are involved, along with the description of seven cases of irreversible renal graft injury due to secondary hyperoxaluria.

Full Text

Duke Authors

Cited Authors

  • Karaolanis, G; Lionaki, S; Moris, D; Palla, V-V; Vernadakis, S

Published Date

  • October 2014

Published In

Volume / Issue

  • 28 / 4

Start / End Page

  • 182 - 187

PubMed ID

  • 24999029

Electronic International Standard Serial Number (EISSN)

  • 1557-9816

International Standard Serial Number (ISSN)

  • 0955-470X

Digital Object Identifier (DOI)

  • 10.1016/j.trre.2014.05.004


  • eng