Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) study: Protocol and baseline characteristics of a randomized controlled trial.
Journal Article (Journal Article;Multicenter Study)
UNLABELLED: Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease (ESKD) in the United States. Multiple risk factors contribute to DKD development, yet few interventions target more than a single DKD risk factor at a time. This manuscript describes the study protocol, recruitment, and baseline participant characteristics for the Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) study. The STOP-DKD study is a randomized controlled trial designed to evaluate the effectiveness of a multifactorial behavioral and medication management intervention to mitigate kidney function decline at 3 years compared to usual care. The intervention consists of up to 36 monthly educational modules delivered via telephone by a study pharmacist, home blood pressure monitoring, and medication management recommendations delivered electronically to primary care physicians. Patients seen at seven primary care clinics in North Carolina, with diabetes and [1] uncontrolled hypertension and [2] evidence of kidney dysfunction (albuminuria or reduced estimated glomerular filtration rate [eGFR]) were eligible to participate. Study recruitment completed in December 2014. Of the 281 participants randomized, mean age at baseline was 61.9; 52% were male, 56% were Black, and most were high school graduates (89%). Baseline co-morbidity was high- mean blood pressure was 134/76 mmHg, mean body mass index was 35.7 kg/m2, mean eGFR was 80.7 ml/min/1.73 m2, and mean glycated hemoglobin was 8.0%. Experiences of recruiting and implementing a comprehensive DKD program to individuals at high risk seen in the primary care setting are provided. TRIAL REGISTRATION: NCT01829256.
Full Text
Duke Authors
- Barnhart, Huiman Xie
- Bosworth, Hayden Barry
- Crowley, Matthew Janik
- Davenport, Tina
- Diamantidis, Clarissa Jonas
- Patel, Uptal Dinesh
- Pendergast, Jane Frances
Cited Authors
- Diamantidis, CJ; Bosworth, HB; Oakes, MM; Davenport, CA; Pendergast, JF; Patel, S; Moaddeb, J; Barnhart, HX; Merrill, PD; Baloch, K; Crowley, MJ; Patel, UD
Published Date
- June 2018
Published In
Volume / Issue
- 69 /
Start / End Page
- 28 - 39
PubMed ID
- 29649631
Pubmed Central ID
- PMC5986182
Electronic International Standard Serial Number (EISSN)
- 1559-2030
Digital Object Identifier (DOI)
- 10.1016/j.cct.2018.04.003
Language
- eng
Conference Location
- United States