Development of a scale for grading pre-plus and plus disease using retinal images: A pilot study.

Journal Article (Journal Article)

When screening infants for retinopathy of prematurity, evaluating posterior pole vascular characteristics (ie, the presence or absence of pre-plus or plus disease) is subjective and prone to error. ROPtool, a semiautomated computer program, measures retinal vessel tortuosity and dilation. In this pilot study, we created an abbreviated pictorial scale of varying vascular tortuosity and dilation based on expert perception of vascular characteristics. We used ROPtool to evaluate the experts' ability to arrange these images in order of increasing vascular tortuosity and dilation. ROPtool values confirmed successful arrangement of images in order of increasing vascular tortuosity and dilation. This pictorial scale could serve as a reference to decrease subjectivity when diagnosing pre-plus or plus disease.

Full Text

Duke Authors

Cited Authors

  • Nasrazadani, DA; Wallace, DK; Freedman, SF; Prakalapakorn, SG

Published Date

  • August 2018

Published In

Volume / Issue

  • 22 / 4

Start / End Page

  • 316 - 319

PubMed ID

  • 29630931

Pubmed Central ID

  • PMC6128736

Electronic International Standard Serial Number (EISSN)

  • 1528-3933

Digital Object Identifier (DOI)

  • 10.1016/j.jaapos.2018.01.007


  • eng

Conference Location

  • United States