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Recent progress in photoacoustic molecular imaging.

Publication ,  Journal Article
Yao, J; Wang, LV
Published in: Current opinion in chemical biology
August 2018

By acoustically detecting the optical absorption contrast, photoacoustic (PA) tomography (PAT) has broken the penetration limits of traditional high-resolution optical imaging. Through spectroscopic analysis of the target's optical absorption, PAT can identify a wealth of endogenous and exogenous molecules and thus is inherently capable of molecular imaging with high sensitivity. PAT's molecular sensitivity is uniquely accompanied by non-ionizing radiation, high spatial resolution, and deep penetration in biological tissues, which other optical imaging modalities cannot achieve yet. In this concise review, we summarize the most recent technological advancements in PA molecular imaging and highlight the novel molecular probes specifically made for PAT in deep tissues. We conclude with a brief discussion of the opportunities for future advancements.

Duke Scholars

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Published In

Current opinion in chemical biology

DOI

EISSN

1879-0402

ISSN

1367-5931

Publication Date

August 2018

Volume

45

Start / End Page

104 / 112

Related Subject Headings

  • Tomography
  • Photoacoustic Techniques
  • Organic Chemistry
  • Molecular Probes
  • Molecular Imaging
  • Humans
  • Equipment Design
  • Animals
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
 

Citation

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MLA
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Yao, J., & Wang, L. V. (2018). Recent progress in photoacoustic molecular imaging. Current Opinion in Chemical Biology, 45, 104–112. https://doi.org/10.1016/j.cbpa.2018.03.016
Yao, Junjie, and Lihong V. Wang. “Recent progress in photoacoustic molecular imaging.Current Opinion in Chemical Biology 45 (August 2018): 104–12. https://doi.org/10.1016/j.cbpa.2018.03.016.
Yao J, Wang LV. Recent progress in photoacoustic molecular imaging. Current opinion in chemical biology. 2018 Aug;45:104–12.
Yao, Junjie, and Lihong V. Wang. “Recent progress in photoacoustic molecular imaging.Current Opinion in Chemical Biology, vol. 45, Aug. 2018, pp. 104–12. Epmc, doi:10.1016/j.cbpa.2018.03.016.
Yao J, Wang LV. Recent progress in photoacoustic molecular imaging. Current opinion in chemical biology. 2018 Aug;45:104–112.
Journal cover image

Published In

Current opinion in chemical biology

DOI

EISSN

1879-0402

ISSN

1367-5931

Publication Date

August 2018

Volume

45

Start / End Page

104 / 112

Related Subject Headings

  • Tomography
  • Photoacoustic Techniques
  • Organic Chemistry
  • Molecular Probes
  • Molecular Imaging
  • Humans
  • Equipment Design
  • Animals
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology