Pleural nodular mesothelial/histiocytic hyperplasia associated with syphilis


Journal Article

© 2018 Nodular mesothelial/histiocytic hyperplasia (NMHH) is a benign reactive phenomenon that can occur at any mesothelial site. We report the case of a 33 year old male who presented with chest pain and a pleural effusion, and after several months of investigation was found to have positive syphilis serology and NMHH of the pleura that was positive for spirochetes on immunohistochemical stain. NHMM has been previously reported to be caused by physical, inflammatory/infectious, or neoplastic irritation of mesothelium at various sites. This is the first reported case of NMHH associated with syphilis.

Full Text

Duke Authors

Cited Authors

  • Berg, KB; Liebling, PD; Kubik, MJ; Attanoos, R; Galateau-Salle, F; Roggli, V; Wick, M; Churg, AM

Published Date

  • September 1, 2018

Published In

Volume / Issue

  • 13 /

Start / End Page

  • 18 - 20

Electronic International Standard Serial Number (EISSN)

  • 2214-3300

Digital Object Identifier (DOI)

  • 10.1016/j.ehpc.2018.03.005

Citation Source

  • Scopus