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Gene therapy for prostate cancer.

Publication ,  Journal Article
Gingrich, JR; Chauhan, RD; Steiner, MS
Published in: Curr Oncol Rep
September 2001

Basic research continues to unravel the molecular complexity of normal and abnormal biologic processes. The development of means to affect the expression level of genes that promote or contribute to cellular transformation, invasion, and metastasis has spawned the concept of gene therapy. This relatively new field seeks to reverse or suspend the pathologic progression of a variety of diseases including the malignant transformation of prostatic epithelial cells. Initial clinical trials for prostate cancer have thus far shown gene therapy to be relatively safe, although definitive evidence of durable therapeutic efficacy remains to be demonstrated. In this article, recent preclinical research, current therapeutic strategies, and recent results of gene therapy clinical trials for the treatment of prostate cancer are reviewed.

Duke Scholars

Published In

Curr Oncol Rep

DOI

ISSN

1523-3790

Publication Date

September 2001

Volume

3

Issue

5

Start / End Page

438 / 447

Location

United States

Related Subject Headings

  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Immunotherapy
  • Humans
  • Genetic Therapy
  • Combined Modality Therapy
  • Clinical Trials as Topic
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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Gingrich, J. R., Chauhan, R. D., & Steiner, M. S. (2001). Gene therapy for prostate cancer. Curr Oncol Rep, 3(5), 438–447. https://doi.org/10.1007/s11912-001-0031-6
Gingrich, J. R., R. D. Chauhan, and M. S. Steiner. “Gene therapy for prostate cancer.Curr Oncol Rep 3, no. 5 (September 2001): 438–47. https://doi.org/10.1007/s11912-001-0031-6.
Gingrich JR, Chauhan RD, Steiner MS. Gene therapy for prostate cancer. Curr Oncol Rep. 2001 Sep;3(5):438–47.
Gingrich, J. R., et al. “Gene therapy for prostate cancer.Curr Oncol Rep, vol. 3, no. 5, Sept. 2001, pp. 438–47. Pubmed, doi:10.1007/s11912-001-0031-6.
Gingrich JR, Chauhan RD, Steiner MS. Gene therapy for prostate cancer. Curr Oncol Rep. 2001 Sep;3(5):438–447.
Journal cover image

Published In

Curr Oncol Rep

DOI

ISSN

1523-3790

Publication Date

September 2001

Volume

3

Issue

5

Start / End Page

438 / 447

Location

United States

Related Subject Headings

  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Immunotherapy
  • Humans
  • Genetic Therapy
  • Combined Modality Therapy
  • Clinical Trials as Topic
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis