How I treat thrombocytopenia in pregnancy.

Journal Article (Journal Article;Review)

A mild thrombocytopenia is relatively frequent during pregnancy and has generally no consequences for either the mother or the fetus. Although representing no threat in the majority of patients, thrombocytopenia may result from a range of pathologic conditions requiring closer monitoring and possible therapy. Two clinical scenarios are particularly relevant for their prevalence and the issues relating to their management. The first is the presence of isolated thrombocytopenia and the differential diagnosis between primary immune thrombocytopenia and gestational thrombocytopenia. The second is thrombocytopenia associated with preeclampsia and its look-alikes and their distinction from thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome. In this review, we describe a systematic approach to the diagnosis and treatment of these disease entities using a case presentation format. Our discussion includes the antenatal and perinatal management of both the mother and fetus.

Full Text

Duke Authors

Cited Authors

  • Gernsheimer, T; James, AH; Stasi, R

Published Date

  • January 3, 2013

Published In

Volume / Issue

  • 121 / 1

Start / End Page

  • 38 - 47

PubMed ID

  • 23149846

Electronic International Standard Serial Number (EISSN)

  • 1528-0020

Digital Object Identifier (DOI)

  • 10.1182/blood-2012-08-448944


  • eng

Conference Location

  • United States