Maternal Dietary Patterns are Associated with Lower Levels of Cardiometabolic Markers during Pregnancy.

Published

Journal Article

BACKGROUND: Elevated levels of cardiometabolic markers are characteristic of normal pregnancy, however, insulin resistance and increased glucose, triglyceride, and cholesterol levels can adversely influence maternal and child health. Diet is a modifiable behaviour that could have significant impact on maternal cardiometabolic levels during pregnancy. We investigated the association between dietary patterns and cardiometabolic markers (glucose, insulin, insulin resistance (HOMA-IR), triglycerides, and cholesterol) during pregnancy. METHODS: Data from the Pregnancy, Infection, and Nutrition prospective cohort study (2000-05) was used (n = 513). Diet was assessed using a food frequency questionnaire. Dietary patterns were derived using latent class analysis (LCA) and the Dietary Approaches to Stop Hypertension (DASH) diet. Linear regression was used to examine the dietary patterns-cardiometabolic markers association during pregnancy. RESULTS: Three dietary patterns evolved from the LCA characterised by high intakes of: (1) hamburgers, hot dogs, bacon, French fries, fried chicken, white bread, and soft drinks; (2) some vegetables, fruit juice, refined grains, mixed dishes, processed meat, and empty calorie foods; and (3) fruits, vegetables, whole grains, low-fat dairy, breakfast bars, and water. After adjustment for potential confounders including prepregnancy body mass index, a diet consistent with Latent Class 3 was negatively associated with maternal insulin (μU/mL: β = -0.12; 95% CI -0.23, -0.01) and HOMA-IR (β = -0.13; 95% CI -0.25, -0.00). Additionally, DASH scores within Tertile 3 (higher dietary quality) were also negatively associated with maternal triglycerides (mg/dL). CONCLUSIONS: The study findings suggest an association between maternal dietary patterns and several cardiometabolic markers during pregnancy.

Full Text

Duke Authors

Cited Authors

  • Martin, CL; Siega-Riz, AM; Sotres-Alvarez, D; Robinson, WR; Daniels, JL; Perrin, EM; Stuebe, AM

Published Date

  • May 2016

Published In

Volume / Issue

  • 30 / 3

Start / End Page

  • 246 - 255

PubMed ID

  • 26848932

Pubmed Central ID

  • 26848932

Electronic International Standard Serial Number (EISSN)

  • 1365-3016

Digital Object Identifier (DOI)

  • 10.1111/ppe.12279

Language

  • eng

Conference Location

  • England