Coronary Artery Disease in Patients ≥80 Years of Age.


Journal Article (Review)

Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients ≥80 years of age. Nonetheless, older patients have typically been under-represented in cardiovascular clinical trials. Understanding the pathophysiology, epidemiology, and optimal means of diagnosis and treatment of CAD in older adults is crucial to improving outcomes in this high-risk population. A patient-centered approach, taking into account health status, functional ability and frailty, cognitive skills, and patient preferences is essential when caring for older adults with CAD. The present systematic review focuses on the current knowledge base, gaps in understanding, and directions for future investigation pertaining to CAD in patients ≥80 years of age.

Full Text

Duke Authors

Cited Authors

  • Madhavan, MV; Gersh, BJ; Alexander, KP; Granger, CB; Stone, GW

Published Date

  • May 8, 2018

Published In

Volume / Issue

  • 71 / 18

Start / End Page

  • 2015 - 2040

PubMed ID

  • 29724356

Pubmed Central ID

  • 29724356

Electronic International Standard Serial Number (EISSN)

  • 1558-3597

Digital Object Identifier (DOI)

  • 10.1016/j.jacc.2017.12.068


  • eng

Conference Location

  • United States