Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer.THERMODOX®.

Journal Article (Journal Article;Review)

Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox®) that enables local accumulation of systemic chemotherapy.

Full Text

Duke Authors

Cited Authors

  • Aminsharifi, A; Brousell, SC; Chang, A; León, J; Inman, BA

Published Date

  • May 2018

Published In

Volume / Issue

  • 71 / 4

Start / End Page

  • 447 - 452

PubMed ID

  • 29745934

International Standard Serial Number (ISSN)

  • 0004-0614


  • spa eng

Conference Location

  • Spain