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Inter-laboratory comparison of channelized hotelling observer computation.

Publication ,  Journal Article
Ba, A; Abbey, CK; Baek, J; Han, M; Bouwman, RW; Balta, C; Brankov, J; Massanes, F; Gifford, HC; Hernandez-Giron, I; Veldkamp, WJH; Petrov, D ...
Published in: Med Phys
July 2018

PURPOSE: The task-based assessment of image quality using model observers is increasingly used for the assessment of different imaging modalities. However, the performance computation of model observers needs standardization as well as a well-established trust in its implementation methodology and uncertainty estimation. The purpose of this work was to determine the degree of equivalence of the channelized Hotelling observer performance and uncertainty estimation using an intercomparison exercise. MATERIALS AND METHODS: Image samples to estimate model observer performance for detection tasks were generated from two-dimensional CT image slices of a uniform water phantom. A common set of images was sent to participating laboratories to perform and document the following tasks: (a) estimate the detectability index of a well-defined CHO and its uncertainty in three conditions involving different sized targets all at the same dose, and (b) apply this CHO to an image set where ground truth was unknown to participants (lower image dose). In addition, and on an optional basis, we asked the participating laboratories to (c) estimate the performance of real human observers from a psychophysical experiment of their choice. Each of the 13 participating laboratories was confidentially assigned a participant number and image sets could be downloaded through a secure server. Results were distributed with each participant recognizable by its number and then each laboratory was able to modify their results with justification as model observer calculation are not yet a routine and potentially error prone. RESULTS: Detectability index increased with signal size for all participants and was very consistent for 6 mm sized target while showing higher variability for 8 and 10 mm sized target. There was one order of magnitude between the lowest and the largest uncertainty estimation. CONCLUSIONS: This intercomparison helped define the state of the art of model observer performance computation and with thirteen participants, reflects openness and trust within the medical imaging community. The performance of a CHO with explicitly defined channels and a relatively large number of test images was consistently estimated by all participants. In contrast, the paper demonstrates that there is no agreement on estimating the variance of detectability in the training and testing setting.

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Published In

Med Phys

DOI

EISSN

2473-4209

Publication Date

July 2018

Volume

45

Issue

7

Start / End Page

3019 / 3030

Location

United States

Related Subject Headings

  • Uncertainty
  • Tomography, X-Ray Computed
  • Observer Variation
  • Nuclear Medicine & Medical Imaging
  • Laboratories
  • Image Processing, Computer-Assisted
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
 

Citation

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ICMJE
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Ba, A., Abbey, C. K., Baek, J., Han, M., Bouwman, R. W., Balta, C., … Bochud, F. O. (2018). Inter-laboratory comparison of channelized hotelling observer computation. Med Phys, 45(7), 3019–3030. https://doi.org/10.1002/mp.12940
Ba, Alexandre, Craig K. Abbey, Jongduk Baek, Minah Han, Ramona W. Bouwman, Christiana Balta, Jovan Brankov, et al. “Inter-laboratory comparison of channelized hotelling observer computation.Med Phys 45, no. 7 (July 2018): 3019–30. https://doi.org/10.1002/mp.12940.
Ba A, Abbey CK, Baek J, Han M, Bouwman RW, Balta C, et al. Inter-laboratory comparison of channelized hotelling observer computation. Med Phys. 2018 Jul;45(7):3019–30.
Ba, Alexandre, et al. “Inter-laboratory comparison of channelized hotelling observer computation.Med Phys, vol. 45, no. 7, July 2018, pp. 3019–30. Pubmed, doi:10.1002/mp.12940.
Ba A, Abbey CK, Baek J, Han M, Bouwman RW, Balta C, Brankov J, Massanes F, Gifford HC, Hernandez-Giron I, Veldkamp WJH, Petrov D, Marshall N, Samuelson FW, Zeng R, Solomon JB, Samei E, Timberg P, Förnvik H, Reiser I, Yu L, Gong H, Bochud FO. Inter-laboratory comparison of channelized hotelling observer computation. Med Phys. 2018 Jul;45(7):3019–3030.

Published In

Med Phys

DOI

EISSN

2473-4209

Publication Date

July 2018

Volume

45

Issue

7

Start / End Page

3019 / 3030

Location

United States

Related Subject Headings

  • Uncertainty
  • Tomography, X-Ray Computed
  • Observer Variation
  • Nuclear Medicine & Medical Imaging
  • Laboratories
  • Image Processing, Computer-Assisted
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering