Contemporary Strategies and Barriers to Transplantation Tolerance.


Journal Article (Review)

The purpose of this review is to discuss immunologic tolerance as it applies to solid organ transplantation and to identify barriers that hinder the achievement of this long-term goal. First, the definition of tolerance and an introduction of mechanisms by which tolerance exists or can be achieved will be discussed. Next, a review of contemporary attempts at achieving transplant tolerance will be described. Finally, a discussion of the humoral barriers to transplantation tolerance and potential ways to overcome these barriers will be presented.

Full Text

Duke Authors

Cited Authors

  • Ezekian, B; Schroder, PM; Freischlag, K; Yoon, J; Kwun, J; Knechtle, SJ

Published Date

  • August 2018

Published In

Volume / Issue

  • 102 / 8

Start / End Page

  • 1213 - 1222

PubMed ID

  • 29757903

Pubmed Central ID

  • 29757903

Electronic International Standard Serial Number (EISSN)

  • 1534-6080

Digital Object Identifier (DOI)

  • 10.1097/TP.0000000000002242


  • eng

Conference Location

  • United States