Contemporary Strategies and Barriers to Transplantation Tolerance.

Journal Article (Journal Article;Review)

The purpose of this review is to discuss immunologic tolerance as it applies to solid organ transplantation and to identify barriers that hinder the achievement of this long-term goal. First, the definition of tolerance and an introduction of mechanisms by which tolerance exists or can be achieved will be discussed. Next, a review of contemporary attempts at achieving transplant tolerance will be described. Finally, a discussion of the humoral barriers to transplantation tolerance and potential ways to overcome these barriers will be presented.

Full Text

Duke Authors

Cited Authors

  • Ezekian, B; Schroder, PM; Freischlag, K; Yoon, J; Kwun, J; Knechtle, SJ

Published Date

  • August 2018

Published In

Volume / Issue

  • 102 / 8

Start / End Page

  • 1213 - 1222

PubMed ID

  • 29757903

Pubmed Central ID

  • PMC6059978

Electronic International Standard Serial Number (EISSN)

  • 1534-6080

Digital Object Identifier (DOI)

  • 10.1097/TP.0000000000002242


  • eng

Conference Location

  • United States