Creation of an optically tunable, solid tissue phantom for use in cancer detection

Conference Paper

An optically tunable, solid tissue phantom was developed in order to aid in the verification and validation of non-destructive cancer detection technologies based on fluorescence spectroscopy. The solid tissue phantom contained agarose, hemoglobin, Intralipid, NADH, and FAD. The redox ratio of the solid phantoms were shown to be tunable; thus, indicating that these phantoms could be used to tailor specific optical conditions that mimic cancerous and healthy tissues. Therefore, this solid tissue phantom can serve as a suitable test bed to evaluate fluorescence spectroscopy based cancer detection devices.

Full Text

Duke Authors

Cited Authors

  • Tucker, MB; Wallace, C; Mantena, S; Cornwell, N; Ross, W; Odion, R; Vo-Dinh, T; Codd, P

Published Date

  • January 1, 2018

Published In

Volume / Issue

  • 10480 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9781510614451

Digital Object Identifier (DOI)

  • 10.1117/12.2290499

Citation Source

  • Scopus