Electrochemistry of redox-active Mn porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ - study of redox species involved in ROS/RNS scavenging
Publication
, Journal Article
Weitner, T; Batinic-Haberle, I
Published in: ADMET and DMPK
September 1, 2014
Manganese ortho tetrakis(N-n-butoxyethylpyridinium-2-yl)porphyrin, MnTnBuOE-2-PyP5+, is a third-generation redox-active compound currently undergoing preclinical exploration. This work is intended to complement the already extensive research of its chemical and biological properties by a simple electrochemical study. The thermodynamic parameters related to the Mn(IV) porphyrin species of MnTnBuOE-2-PyP5+ determined in this work support its observed reactivity as an efficient scavenger of peroxynitrite. The corresponding driving forces for the possible single-electron or two-electron reductions of ONOO- have been estimated as well.
Duke Scholars
Published In
ADMET and DMPK
DOI
EISSN
1848-7718
Publication Date
September 1, 2014
Volume
2
Issue
3
Start / End Page
185 / 190
Citation
APA
Chicago
ICMJE
MLA
NLM
Weitner, T., & Batinic-Haberle, I. (2014). Electrochemistry of redox-active Mn porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ - study of redox species involved in ROS/RNS scavenging. ADMET and DMPK, 2(3), 185–190. https://doi.org/10.5599/admet.2.3.123
Weitner, T., and I. Batinic-Haberle. “Electrochemistry of redox-active Mn porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ - study of redox species involved in ROS/RNS scavenging.” ADMET and DMPK 2, no. 3 (September 1, 2014): 185–90. https://doi.org/10.5599/admet.2.3.123.
Weitner T, Batinic-Haberle I. Electrochemistry of redox-active Mn porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ - study of redox species involved in ROS/RNS scavenging. ADMET and DMPK. 2014 Sep 1;2(3):185–90.
Weitner, T., and I. Batinic-Haberle. “Electrochemistry of redox-active Mn porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ - study of redox species involved in ROS/RNS scavenging.” ADMET and DMPK, vol. 2, no. 3, Sept. 2014, pp. 185–90. Scopus, doi:10.5599/admet.2.3.123.
Weitner T, Batinic-Haberle I. Electrochemistry of redox-active Mn porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ - study of redox species involved in ROS/RNS scavenging. ADMET and DMPK. 2014 Sep 1;2(3):185–190.
Published In
ADMET and DMPK
DOI
EISSN
1848-7718
Publication Date
September 1, 2014
Volume
2
Issue
3
Start / End Page
185 / 190