Oscillation patterns of local field potentials in the dorsal striatum and sensorimotor cortex during the encoding, maintenance, and decision stages for the ordinal comparison of sub- and supra-second signal durations.

Published

Journal Article (Review)

Ordinal comparison of successively presented signal durations requires (a) the encoding of the first signal duration (standard), (b) maintenance of temporal information specific to the standard duration in memory, and (c) timing of the second signal duration (comparison) during which a comparison is made of the first and second durations. Rats were first trained to make ordinal comparisons of signal durations within three time ranges using 0.5, 1.0, and 3.0-s standard durations. Local field potentials were then recorded from the dorsal striatum and sensorimotor cortex in order to investigate the pattern of neural oscillations during each phase of the ordinal-comparison process. Increased power in delta and theta frequency ranges was observed during both the encoding and comparison stages. Active maintenance of a selected response, "shorter" or "longer" (counter-balanced across left and right levers), was represented by an increase of theta and delta oscillations in the contralateral striatum and cortex. Taken together, these data suggest that neural oscillations in the delta-theta range play an important role in the encoding, maintenance, and comparison of signal durations.

Full Text

Duke Authors

Cited Authors

  • Gu, B-M; Kukreja, K; Meck, WH

Published Date

  • September 2018

Published In

Volume / Issue

  • 153 / Pt A

Start / End Page

  • 79 - 91

PubMed ID

  • 29778763

Pubmed Central ID

  • 29778763

Electronic International Standard Serial Number (EISSN)

  • 1095-9564

International Standard Serial Number (ISSN)

  • 1074-7427

Digital Object Identifier (DOI)

  • 10.1016/j.nlm.2018.05.003

Language

  • eng