Early Life HIV-1 Immunization: Providing a Window for Protection Before Sexual Debut.


Journal Article

Limited success of current HIV-1 vaccines warrants new approaches. We discuss feasibility and potential benefits of early life HIV-1 immunization followed by vaccine boosts during childhood that may enable maturation of vaccine-induced broad anti-HIV-1 immunity over several years. By initiating this immunization approach in the very young, well before sexual debut, such a strategy may dramatically reduce the risk of HIV-1 infection.

Full Text

Duke Authors

Cited Authors

  • Permar, S; Levy, O; Kollman, TR; Singh, A; De Paris, K

Published Date

  • October 2018

Published In

Volume / Issue

  • 34 / 10

Start / End Page

  • 823 - 827

PubMed ID

  • 29860868

Pubmed Central ID

  • 29860868

Electronic International Standard Serial Number (EISSN)

  • 1931-8405

Digital Object Identifier (DOI)

  • 10.1089/AID.2018.0018


  • eng

Conference Location

  • United States