Detection of novel astroviruses in urban brown rats and previously known astroviruses in humans.


Journal Article

Several novel astroviruses have been recently discovered in humans and in other animals. Here, we report results from our surveillance of astroviruses in human and rodent faecal samples in Hong Kong. Classical human astroviruses (n=9) and a human MLB1 astrovirus were detected in human faecal samples (n=622). Novel astroviruses were detected from 1.6 % of the faecal samples of urban brown rat (Rattus norvegicus) (n=441), indicating the prevalence of astrovirus infection in rats might be much lower than that recently observed in bats. These rat astroviruses were phylogenetically related to recently discovered human astroviruses MLB1 and MLB2, suggesting that the MLB viruses and these novel rat astroviruses may share a common ancestor.

Full Text

Cited Authors

  • Chu, DKW; Chin, AWH; Smith, GJ; Chan, K-H; Guan, Y; Peiris, JSM; Poon, LLM

Published Date

  • October 2010

Published In

Volume / Issue

  • 91 / Pt 10

Start / End Page

  • 2457 - 2462

PubMed ID

  • 20554799

Pubmed Central ID

  • 20554799

Electronic International Standard Serial Number (EISSN)

  • 1465-2099

International Standard Serial Number (ISSN)

  • 0022-1317

Digital Object Identifier (DOI)

  • 10.1099/vir.0.022764-0


  • eng