Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Journal Article (Academic article)

We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

Full Text

Duke Authors

Cited Authors

  • Abbaspourrad, A; Duncanson, WJ; Lebedeva, N; Kim, SH; Zhushma, AP; Datta, SS; Dayton, PA; Sheiko, SS; Rubinstein, M; Weitz, DA

Published Date

  • 2013

Published In

International Standard Serial Number (ISSN)

  • 0743-7463

Digital Object Identifier (DOI)

  • 10.1021/la402598p