Active two-channel 0.035'' guidewire for interventional cardiovascular MRI.


Journal Article

PURPOSE: To develop an "active" (receiver-coil) clinical-grade guidewire with enhanced visibility for magnetic resonance imaging (MRI) and favorable mechanical characteristics for interventional MRI procedures that require conspicuous intravascular instruments distinguishable from surrounding tissues. MATERIALS AND METHODS: We designed a 0.035-inch guidewire combining two antenna designs on separate channels. A loop antenna visualizes the tip and a dipole antenna visualizes the whole shaft. We compared mechanical characteristics of this guidewire with x-ray alternatives and tested MRI performance at 1.5T in vitro and in vivo in swine. RESULTS: Images reflected tip position within 0.97 +/- 0.42 mm and afforded whole-shaft visibility under expected conditions without sacrificing device size or handling. We report tip stiffness, torquability, and pushability comparable to commercial interventional guidewires. CONCLUSION: Our clinical-grade 0.035-inch active guidewire is conspicuous under MRI and has mechanical performance comparable to x-ray interventional guidewires. This may enable a range of interventional procedures using real-time MRI.

Full Text

Cited Authors

  • Kocaturk, O; Kim, AH; Saikus, CE; Guttman, MA; Faranesh, AZ; Ozturk, C; Lederman, RJ

Published Date

  • August 2009

Published In

Volume / Issue

  • 30 / 2

Start / End Page

  • 461 - 465

PubMed ID

  • 19629968

Pubmed Central ID

  • 19629968

International Standard Serial Number (ISSN)

  • 1053-1807

Digital Object Identifier (DOI)

  • 10.1002/jmri.21844


  • eng

Conference Location

  • United States