Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT.

Journal Article (Journal Article)

Ophthalmic procedures demand precise surgical instrument control in depth, yet standard operating microscopes supply limited depth perception. Current commercial microscope-integrated optical coherence tomography partially meets this need with manually-positioned cross-sectional images that offer qualitative estimates of depth. In this work, we present methods for automatic quantitative depth measurement using real-time, two-surface corneal segmentation and needle tracking in OCT volumes. We then demonstrate these methods for guidance of ex vivo deep anterior lamellar keratoplasty (DALK) needle insertions. Surgeons using the output of these methods improved their ability to reach a target depth, and decreased their incidence of corneal perforations, both with statistical significance. We believe these methods could increase the success rate of DALK and thereby improve patient outcomes.

Full Text

Duke Authors

Cited Authors

  • Keller, B; Draelos, M; Tang, G; Farsiu, S; Kuo, AN; Hauser, K; Izatt, JA

Published Date

  • June 1, 2018

Published In

Volume / Issue

  • 9 / 6

Start / End Page

  • 2716 - 2732

PubMed ID

  • 30258685

Pubmed Central ID

  • PMC6154196

International Standard Serial Number (ISSN)

  • 2156-7085

Digital Object Identifier (DOI)

  • 10.1364/BOE.9.002716


  • eng

Conference Location

  • United States