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Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.

Publication ,  Journal Article
Le Maréchal, M; Tebano, G; Monnier, AA; Adriaenssens, N; Gyssens, IC; Huttner, B; Milanic, R; Schouten, J; Stanic Benic, M; Versporten, A ...
Published in: J Antimicrob Chemother
June 1, 2018

OBJECTIVES: Quality indicators (QIs) assessing the appropriateness of antibiotic use are essential to identify targets for improvement and guide antibiotic stewardship interventions. The aim of this study was to develop a set of QIs for the outpatient setting from a global perspective. METHODS: A systematic literature review was performed by searching MEDLINE and relevant web sites in order to retrieve a list of QIs. These indicators were extracted from published trials, guidelines, literature reviews or consensus procedures. This evidence-based set of QIs was evaluated by a multidisciplinary, international group of stakeholders using a RAND-modified Delphi procedure, using two online questionnaires and a face-to-face meeting between them. Stakeholders appraised the QIs' relevance using a nine-point Likert scale. This work is part of the DRIVE-AB project. RESULTS: The systematic literature review identified 43 unique QIs, from 54 studies and seven web sites. Twenty-five stakeholders from 14 countries participated in the consensus procedure. Ultimately, 32 QIs were retained, with a high level of agreement. The set of QIs included structure, process and outcome indicators, targeting both high- and middle- to low-income settings. Most indicators focused on general practice, addressing the common indications for antibiotic use in the community (particularly urinary and respiratory tract infections), and the organization of healthcare facilities. Twelve indicators specifically addressed outpatient parenteral antimicrobial therapy (OPAT). CONCLUSIONS: We identified a set of 32 outpatient QIs to measure the appropriateness of antibiotic use. These QIs can be used to identify targets for improvement and to evaluate the effects of antibiotic stewardship interventions.

Duke Scholars

Published In

J Antimicrob Chemother

DOI

EISSN

1460-2091

Publication Date

June 1, 2018

Volume

73

Issue

suppl_6

Start / End Page

vi40 / vi49

Location

England

Related Subject Headings

  • Surveys and Questionnaires
  • Stakeholder Participation
  • Respiratory Tract Infections
  • Quality Indicators, Health Care
  • Public Health
  • Outpatients
  • Microbiology
  • Internationality
  • Humans
  • Consensus
 

Citation

APA
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ICMJE
MLA
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Le Maréchal, M., Tebano, G., Monnier, A. A., Adriaenssens, N., Gyssens, I. C., Huttner, B., … DRIVE-AB WP1 group, . (2018). Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure. J Antimicrob Chemother, 73(suppl_6), vi40–vi49. https://doi.org/10.1093/jac/dky117
Le Maréchal, Marion, Gianpiero Tebano, Annelie A. Monnier, Niels Adriaenssens, Inge C. Gyssens, Benedikt Huttner, Romina Milanic, et al. “Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.J Antimicrob Chemother 73, no. suppl_6 (June 1, 2018): vi40–49. https://doi.org/10.1093/jac/dky117.
Le Maréchal M, Tebano G, Monnier AA, Adriaenssens N, Gyssens IC, Huttner B, et al. Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure. J Antimicrob Chemother. 2018 Jun 1;73(suppl_6):vi40–9.
Le Maréchal, Marion, et al. “Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.J Antimicrob Chemother, vol. 73, no. suppl_6, June 2018, pp. vi40–49. Pubmed, doi:10.1093/jac/dky117.
Le Maréchal M, Tebano G, Monnier AA, Adriaenssens N, Gyssens IC, Huttner B, Milanic R, Schouten J, Stanic Benic M, Versporten A, Vlahovic-Palcevski V, Zanichelli V, Hulscher ME, Pulcini C, DRIVE-AB WP1 group. Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure. J Antimicrob Chemother. 2018 Jun 1;73(suppl_6):vi40–vi49.
Journal cover image

Published In

J Antimicrob Chemother

DOI

EISSN

1460-2091

Publication Date

June 1, 2018

Volume

73

Issue

suppl_6

Start / End Page

vi40 / vi49

Location

England

Related Subject Headings

  • Surveys and Questionnaires
  • Stakeholder Participation
  • Respiratory Tract Infections
  • Quality Indicators, Health Care
  • Public Health
  • Outpatients
  • Microbiology
  • Internationality
  • Humans
  • Consensus