Executive summary of AAPM Report Task Group 113: Guidance for the physics aspects of clinical trials.

Journal Article (Journal Article)

The charge of AAPM Task Group 113 is to provide guidance for the physics aspects of clinical trials to minimize variability in planning and dose delivery for external beam trials involving photons and electrons. Several studies have demonstrated the importance of protocol compliance on patient outcome. Minimizing variability for treatments at different centers improves the quality and efficiency of clinical trials. Attention is focused on areas where variability can be minimized through standardization of protocols and processes through all aspects of clinical trials. Recommendations are presented for clinical trial designers, physicists supporting clinical trials at their individual clinics, quality assurance centers, and manufacturers.

Full Text

Duke Authors

Cited Authors

  • Moran, JM; Molineu, A; Kruse, JJ; Oldham, M; Jeraj, R; Galvin, JM; Palta, JR; Olch, AJ

Published Date

  • September 2018

Published In

Volume / Issue

  • 19 / 5

Start / End Page

  • 335 - 346

PubMed ID

  • 29959816

Pubmed Central ID

  • PMC6123105

Electronic International Standard Serial Number (EISSN)

  • 1526-9914

Digital Object Identifier (DOI)

  • 10.1002/acm2.12384


  • eng

Conference Location

  • United States