A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions.

Journal Article (Journal Article)

Human T-cell lymphotropic virus (HTLV), an infection that is endemic in certain parts of Asia, Africa, and South America, has been associated with malignancy and neurological deficits. Here, we describe a pediatric patient with chronic HTLV-I infection who developed complications associated with HTLV-I (ie, adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis). To our knowledge, this presentation in a child has never been described. The patient underwent a bone marrow transplant and, at the time of this writing, was in remission. This case report highlights the fact that HTLV-related complications, previously expected to occur after decades of infection, also can occur in pediatric patients, particularly those who acquired HTLV-I perinatally.

Full Text

Duke Authors

Cited Authors

  • Akinboyo, IC; Crane, GM; Chen, L; Arav-Boger, R

Published Date

  • December 3, 2018

Published In

Volume / Issue

  • 7 / 4

Start / End Page

  • 350 - 354

PubMed ID

  • 29373673

Pubmed Central ID

  • PMC6276027

Electronic International Standard Serial Number (EISSN)

  • 2048-7207

Digital Object Identifier (DOI)

  • 10.1093/jpids/pix101


  • eng

Conference Location

  • England