Merkel Cell Carcinoma, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology.

Journal Article (Journal Article)

This selection from the NCCN Guidelines for Merkel Cell Carcinoma (MCC) focuses on areas impacted by recently emerging data, including sections describing MCC risk factors, diagnosis, workup, follow-up, and management of advanced disease with radiation and systemic therapy. Included in these sections are discussion of the new recommendations for use of Merkel cell polyomavirus as a biomarker and new recommendations for use of checkpoint immunotherapies to treat metastatic or unresectable disease. The next update of the complete version of the NCCN Guidelines for MCC will include more detailed information about elements of pathology and addresses additional aspects of management of MCC, including surgical management of the primary tumor and draining nodal basin, radiation therapy as primary treatment, and management of recurrence.

Full Text

Duke Authors

Cited Authors

  • Bichakjian, CK; Olencki, T; Aasi, SZ; Alam, M; Andersen, JS; Blitzblau, R; Bowen, GM; Contreras, CM; Daniels, GA; Decker, R; Farma, JM; Fisher, K; Gastman, B; Ghosh, K; Grekin, RC; Grossman, K; Ho, AL; Lewis, KD; Loss, M; Lydiatt, DD; Messina, J; Nehal, KS; Nghiem, P; Puzanov, I; Schmults, CD; Shaha, AR; Thomas, V; Xu, YG; Zic, JA; Hoffmann, KG; Engh, AM

Published Date

  • June 2018

Published In

Volume / Issue

  • 16 / 6

Start / End Page

  • 742 - 774

PubMed ID

  • 29891526

Pubmed Central ID

  • PMC9440150

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2018.0055


  • eng

Conference Location

  • United States