Skip to main content

Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression.

Publication ,  Journal Article
Rutter, EM; Langdale, CL; Hokanson, JA; Hamilton, F; Tran, H; Grill, WM; Flores, KB
Published in: IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
August 2018

Bladder overactivity and incontinence and dysfunction can be mitigated by electrical stimulation of the pudendal nerve applied at the onset of a bladder contraction. Thus, it is important to predict accurately both bladder pressure and the onset of bladder contractions. We propose a novel method for prediction of bladder pressure using a time-dependent spectrogram representation of external urethral sphincter electromyographic (EUS EMG) activity and a least absolute shrinkage and selection operator regression model. There was a statistically significant improvement in prediction of bladder pressure compared with methods based on the firing rate of EUS EMG activity. This approach enabled prediction of the onset of bladder contractions with 91% specificity and 96% sensitivity and may be suitable for closed-loop control of bladder continence.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society

DOI

EISSN

1558-0210

ISSN

1534-4320

Publication Date

August 2018

Volume

26

Issue

8

Start / End Page

1636 / 1644

Related Subject Headings

  • Urinary Incontinence
  • Urinary Bladder
  • Urethra
  • Rats, Wistar
  • Rats
  • Pudendal Nerve
  • Muscle Contraction
  • Models, Theoretical
  • Female
  • Electromyography
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Rutter, E. M., Langdale, C. L., Hokanson, J. A., Hamilton, F., Tran, H., Grill, W. M., & Flores, K. B. (2018). Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression. IEEE Transactions on Neural Systems and Rehabilitation Engineering : A Publication of the IEEE Engineering in Medicine and Biology Society, 26(8), 1636–1644. https://doi.org/10.1109/tnsre.2018.2854675
Rutter, Erica M., Christopher L. Langdale, James A. Hokanson, Franz Hamilton, Hien Tran, Warren M. Grill, and Kevin B. Flores. “Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression.IEEE Transactions on Neural Systems and Rehabilitation Engineering : A Publication of the IEEE Engineering in Medicine and Biology Society 26, no. 8 (August 2018): 1636–44. https://doi.org/10.1109/tnsre.2018.2854675.
Rutter EM, Langdale CL, Hokanson JA, Hamilton F, Tran H, Grill WM, et al. Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. 2018 Aug;26(8):1636–44.
Rutter, Erica M., et al. “Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression.IEEE Transactions on Neural Systems and Rehabilitation Engineering : A Publication of the IEEE Engineering in Medicine and Biology Society, vol. 26, no. 8, Aug. 2018, pp. 1636–44. Epmc, doi:10.1109/tnsre.2018.2854675.
Rutter EM, Langdale CL, Hokanson JA, Hamilton F, Tran H, Grill WM, Flores KB. Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. 2018 Aug;26(8):1636–1644.

Published In

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society

DOI

EISSN

1558-0210

ISSN

1534-4320

Publication Date

August 2018

Volume

26

Issue

8

Start / End Page

1636 / 1644

Related Subject Headings

  • Urinary Incontinence
  • Urinary Bladder
  • Urethra
  • Rats, Wistar
  • Rats
  • Pudendal Nerve
  • Muscle Contraction
  • Models, Theoretical
  • Female
  • Electromyography