Viral Infection "Interferes" with Glucose Tolerance.


Journal Article

In this issue of Immunity, Ε estan et al. (2018) show that viral-induced inflammation leads to insulin resistance in skeletal muscle, followed by compensatory hyperinsulinemia, which promotes the anti-viral effector response of CD8+ T cells. Interestingly, this leads to persistent glucose intolerance and the progression of type 2 diabetes in pre-diabetic animals.

Full Text

Duke Authors

Cited Authors

  • Kiernan, K; MacIver, NJ

Published Date

  • July 17, 2018

Published In

Volume / Issue

  • 49 / 1

Start / End Page

  • 6 - 8

PubMed ID

  • 30021147

Pubmed Central ID

  • 30021147

Electronic International Standard Serial Number (EISSN)

  • 1097-4180

Digital Object Identifier (DOI)

  • 10.1016/j.immuni.2018.06.013


  • eng

Conference Location

  • United States