Pressure Pain Phenotypes in Women Before Breast Cancer Treatment.


Journal Article

OBJECTIVES:To explore associations between quantitative sensory testing (QST) and pretreatment pain, physical, and psychological characteristics in women with breast cancer. SAMPLE & SETTING:41 women with treatment-naive stage 0-III breast cancer at the University of Michigan Comprehensive Cancer Center in Ann Arbor. METHODS & VARIABLES:Participants completed self-report surveys and QST within the month before breast surgery. Pressure pain thresholds (PPTs) were measured bilaterally at each trapezius with a manual QST algometer. PPT values were split, yielding low, moderate, and high pain sensitivity subgroups. Subgroup self-reported characteristics were compared using Spearman's correlation, chi-square, and one-way analysis of variance. RESULTS:Lower PPT (higher sensitivity) was associated with higher levels of pain interference and maladaptive pain cognitions. The high-sensitivity group reported higher pain severities, interference, and catastrophizing and lower belief in internal locus of pain control than the low-sensitivity group. IMPLICATIONS FOR NURSING:Individualized interventions for maladaptive pain cognitions before surgery may reduce pain sensitivity and the severity of chronic pain developed after surgery.

Full Text

Cited Authors

  • Kanzawa-Lee, GA; Harte, SE; Bridges, CM; Brummett, C; Clauw, DJ; Williams, DA; Knoerl, R; Lavoie Smith, EM

Published Date

  • July 2018

Published In

Volume / Issue

  • 45 / 4

Start / End Page

  • 483 - 495

PubMed ID

  • 29947358

Pubmed Central ID

  • 29947358

Electronic International Standard Serial Number (EISSN)

  • 1538-0688

International Standard Serial Number (ISSN)

  • 0190-535X

Digital Object Identifier (DOI)

  • 10.1188/18.onf.483-495


  • eng