Contemporary Approaches to In-Transit Melanoma.

Journal Article (Journal Article;Review)

In-transit melanoma represents a distinct disease pattern of heterogeneous superficial tumors. Many treatments have been developed specifically for this type of disease, including regional chemotherapy and a variety of directly injectable agents. Novel strategies include the intralesional delivery of oncolytic viruses and immunocytokines. The combination of intralesional or regional chemotherapy with systemic immune checkpoint inhibitors also is a promising approach. In the current review, we examine the general management of the workup of patients with in-transit disease, the range of available therapies, and recommendations for specific therapies for an individual patient.

Full Text

Duke Authors

Cited Authors

  • Perone, JA; Farrow, N; Tyler, DS; Beasley, GM

Published Date

  • May 2018

Published In

Volume / Issue

  • 14 / 5

Start / End Page

  • 292 - 300

PubMed ID

  • 29746804

Pubmed Central ID

  • PMC5952330

Electronic International Standard Serial Number (EISSN)

  • 1935-469X

Digital Object Identifier (DOI)

  • 10.1200/JOP.18.00063


  • eng

Conference Location

  • United States