The role of sodium intake in nephrolithiasis: epidemiology, pathogenesis, and future directions.
Published
Journal Article (Review)
The prevalence of nephrolithiasis has doubled over the last decade and the incidence in females now approaches that of males. Since dietary salt is lithogenic, a purported mechanism common to both genders is excess dietary sodium intake vis-a-vis processed and fast foods. Nephrolithiasis has far-reaching societal implications such as impact on gross domestic product due to days lost from work (stone disease commonly affects working adults), population-wide carcinogenic diagnostic and interventional radiation exposure (kidney stone disease is typically imaged with computed tomographic imaging and treated under imaging guidance and follow-up), and rising healthcare costs (surgical treatment will be indicated for a number of these patients). Therefore, primary prevention of kidney stone disease via dietary intervention is a low-cost public health initiative with massive societal implications. This primer aims to establish baseline epidemiologic and pathophysiologic principles to guide clinicians in sodium-directed primary prevention of kidney stone disease.
Full Text
Duke Authors
Cited Authors
- Afsar, B; Kiremit, MC; Sag, AA; Tarim, K; Acar, O; Esen, T; Solak, Y; Covic, A; Kanbay, M
Published Date
- November 2016
Published In
Volume / Issue
- 35 /
Start / End Page
- 16 - 19
PubMed ID
- 27444735
Pubmed Central ID
- 27444735
Electronic International Standard Serial Number (EISSN)
- 1879-0828
Digital Object Identifier (DOI)
- 10.1016/j.ejim.2016.07.001
Language
- eng
Conference Location
- Netherlands