Atherosclerotic renal artery stenosis in the post-CORAL era part 2: new directions in Transcatheter Nephron Salvage following flawed revascularization trials.

Journal Article (Journal Article;Review)

Unlike endovascular therapeutic studies for atherosclerosis in many other vascular beds, major trials regarding endovascular renovascular revascularization have resulted in a stagnating equipoise. However, every major trial completed for this topic thus far has suffered from major methodological flaws that limit the validity and external generalizability of their results. Furthermore, certain patient populations who are known to benefit from renovascular revascularization may never be studied because they cannot be ethically withheld from life-saving treatment. Forthcoming percutaneous techniques may one day complement angioplasty and stenting in a burgeoning era of cellular modulation and endovascular-directed renal regeneration.

Full Text

Duke Authors

Cited Authors

  • Sag, AA; Sos, TA; Benli, C; Sal, O; Rossignol, P; Ortiz, A; Solak, Y; Kanbay, M

Published Date

  • April 2016

Published In

Volume / Issue

  • 10 / 4

Start / End Page

  • 368 - 377

PubMed ID

  • 26996432

Electronic International Standard Serial Number (EISSN)

  • 1878-7436

Digital Object Identifier (DOI)

  • 10.1016/j.jash.2016.02.005


  • eng

Conference Location

  • United States