Clinical imaging of vascular disease in chronic kidney disease.

Journal Article (Journal Article;Review)

Arterial wall calcification, once considered an incidental finding, is now known to be a consistent and strong predictor of cardiovascular events in patients with chronic renal insufficiency. It is also commonly encountered in radiologic examinations as an incidental finding. Forthcoming bench, translational, and clinical data seek to establish this and pre-calcification changes as surrogate imaging biomarkers for noninvasive prognostication and treatment follow-up. Emerging paradigms seek to establish vascular calcification as a surrogate marker of disease. Imaging of pre-calcification and decalcification events may prove more important than imaging of the calcification itself. Data-driven approaches to screening will be necessary to limit radiation exposure and prevent over-utilization of expensive imaging techniques.

Full Text

Duke Authors

Cited Authors

  • Sag, AA; Covic, A; London, G; Vervloet, M; Goldsmith, D; Gorriz, JL; Kanbay, M

Published Date

  • June 2016

Published In

Volume / Issue

  • 48 / 6

Start / End Page

  • 827 - 837

PubMed ID

  • 26898824

Electronic International Standard Serial Number (EISSN)

  • 1573-2584

Digital Object Identifier (DOI)

  • 10.1007/s11255-016-1240-0


  • eng

Conference Location

  • Netherlands