T1 hyperintense disc in alkaptonuria.

Published

Journal Article

STUDY DESIGN: Case report. OBJECTIVE: To report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation. SUMMARY OF BACKGROUND DATA: A 46-year-old man without previous diagnosis of alkaptonuria underwent evaluation for progressive back pain revealing a T1-hyperintense disc herniation at the L3-L4 level. Discectomy recovered a blackened disc that was pathologically confirmed to be nucleus pulposus with alkaptonuric involvement. The differential diagnosis of a T1-hyperintense, T2-hypointense disc on magnetic resonance imaging is discussed, with emphasis on the pathophysiology of alkaptonuria. METHODS: A single patient is reported. RESULTS: Pathologically proven patient presentation with radiological and pathological images. CONCLUSION: We report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation.

Full Text

Duke Authors

Cited Authors

  • Sag, AA; Silbergleit, R; Olson, RE; Wilson, J; Krishnan, A

Published Date

  • October 1, 2012

Published In

Volume / Issue

  • 37 / 21

Start / End Page

  • E1361 - E1363

PubMed ID

  • 22772574

Pubmed Central ID

  • 22772574

Electronic International Standard Serial Number (EISSN)

  • 1528-1159

Digital Object Identifier (DOI)

  • 10.1097/BRS.0b013e318266e4ab

Language

  • eng

Conference Location

  • United States