T1 hyperintense disc in alkaptonuria.
Journal Article (Journal Article)
STUDY DESIGN: Case report. OBJECTIVE: To report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation. SUMMARY OF BACKGROUND DATA: A 46-year-old man without previous diagnosis of alkaptonuria underwent evaluation for progressive back pain revealing a T1-hyperintense disc herniation at the L3-L4 level. Discectomy recovered a blackened disc that was pathologically confirmed to be nucleus pulposus with alkaptonuric involvement. The differential diagnosis of a T1-hyperintense, T2-hypointense disc on magnetic resonance imaging is discussed, with emphasis on the pathophysiology of alkaptonuria. METHODS: A single patient is reported. RESULTS: Pathologically proven patient presentation with radiological and pathological images. CONCLUSION: We report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation.
Full Text
Duke Authors
Cited Authors
- Sag, AA; Silbergleit, R; Olson, RE; Wilson, J; Krishnan, A
Published Date
- October 1, 2012
Published In
Volume / Issue
- 37 / 21
Start / End Page
- E1361 - E1363
PubMed ID
- 22772574
Electronic International Standard Serial Number (EISSN)
- 1528-1159
Digital Object Identifier (DOI)
- 10.1097/BRS.0b013e318266e4ab
Language
- eng
Conference Location
- United States