Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme.
Journal Article (Journal Article)
Glioblastoma multiforme is an aggressive malignant brain tumor. The monoclonal antibody, bevacizumab, is active in recurrent disease via inhibition of angiogenesis. Proteinuria and renal thrombotic microangiopathy are known complications. We report a case of a patient developing acute renal failure with biopsy-proven interstitial nephritis while receiving bevacizumab for recurrent disease. The patient was otherwise well with a history of controlled hypertension. Renal function improved with discontinuation of bevacizumab and the administration of corticosteroid therapy.
Full Text
Duke Authors
Cited Authors
- Lomax, AJ; Hill, PA; Ashley, DM
Published Date
- December 2013
Published In
Volume / Issue
- 19 / 4
Start / End Page
- 365 - 368
PubMed ID
- 23235917
Electronic International Standard Serial Number (EISSN)
- 1477-092X
Digital Object Identifier (DOI)
- 10.1177/1078155212466421
Language
- eng
Conference Location
- England