Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme.
Publication
, Journal Article
Lomax, AJ; Hill, PA; Ashley, DM
Published in: J Oncol Pharm Pract
December 2013
Glioblastoma multiforme is an aggressive malignant brain tumor. The monoclonal antibody, bevacizumab, is active in recurrent disease via inhibition of angiogenesis. Proteinuria and renal thrombotic microangiopathy are known complications. We report a case of a patient developing acute renal failure with biopsy-proven interstitial nephritis while receiving bevacizumab for recurrent disease. The patient was otherwise well with a history of controlled hypertension. Renal function improved with discontinuation of bevacizumab and the administration of corticosteroid therapy.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
J Oncol Pharm Pract
DOI
EISSN
1477-092X
Publication Date
December 2013
Volume
19
Issue
4
Start / End Page
365 / 368
Location
England
Related Subject Headings
- Oncology & Carcinogenesis
- Nephritis, Interstitial
- Neoplasm Recurrence, Local
- Middle Aged
- Male
- Humans
- Glucocorticoids
- Glioblastoma
- Brain Neoplasms
- Biopsy
Citation
APA
Chicago
ICMJE
MLA
NLM
Lomax, A. J., Hill, P. A., & Ashley, D. M. (2013). Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme. J Oncol Pharm Pract, 19(4), 365–368. https://doi.org/10.1177/1078155212466421
Lomax, Anna J., Prue A. Hill, and David M. Ashley. “Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme.” J Oncol Pharm Pract 19, no. 4 (December 2013): 365–68. https://doi.org/10.1177/1078155212466421.
Lomax AJ, Hill PA, Ashley DM. Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme. J Oncol Pharm Pract. 2013 Dec;19(4):365–8.
Lomax, Anna J., et al. “Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme.” J Oncol Pharm Pract, vol. 19, no. 4, Dec. 2013, pp. 365–68. Pubmed, doi:10.1177/1078155212466421.
Lomax AJ, Hill PA, Ashley DM. Case report of interstitial nephritis induced by bevacizumab therapy for glioblastoma multiforme. J Oncol Pharm Pract. 2013 Dec;19(4):365–368.
Published In
J Oncol Pharm Pract
DOI
EISSN
1477-092X
Publication Date
December 2013
Volume
19
Issue
4
Start / End Page
365 / 368
Location
England
Related Subject Headings
- Oncology & Carcinogenesis
- Nephritis, Interstitial
- Neoplasm Recurrence, Local
- Middle Aged
- Male
- Humans
- Glucocorticoids
- Glioblastoma
- Brain Neoplasms
- Biopsy