Body composition and serum prostate-specific antigen: review and findings from Flint Men's Health Study.


Journal Article (Review)

Recent studies have suggested that obesity is associated with lower serum prostate-specific antigen levels, perhaps influencing the recommendation for prostate biopsy and potentially explaining part of the observed poorer prognosis among obese men. African-American men have the greatest rates of prostate cancer and are more likely to die of the disease, making early detection a priority in this group. We present findings from the Flint Men's Health Study, a study of African-American men, that are consistent with most studies suggesting that overweight men have prostate-specific antigen levels that are 0.15 to 0.30 ng/mL lower than those who are not overweight. We have coupled our results with a systematic review of publications in this area.

Full Text

Duke Authors

Cited Authors

  • Beebe-Dimmer, JL; Faerber, GJ; Morgenstern, H; Werny, D; Wojno, K; Halstead-Nussloch, B; Cooney, KA

Published Date

  • April 2008

Published In

Volume / Issue

  • 71 / 4

Start / End Page

  • 554 - 560

PubMed ID

  • 18308373

Pubmed Central ID

  • 18308373

Electronic International Standard Serial Number (EISSN)

  • 1527-9995

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2007.11.049


  • eng

Conference Location

  • United States