Metastatic dedifferentiated chordoma with elevated beta-hCG: a case report.

Journal Article (Journal Article)

Chordomas are relatively uncommon bone tumors, and fewer than 10% of cases are classified as dedifferentiated chordomas. These tumors tend to be more clinically aggressive than chordomas and have a higher incidence of early distant metastases. In this case report, we describe a 24-year-old man with dedifferentiated chordoma and multiple pulmonary metastases. Further laboratory analysis revealed an elevated serum beta-human chorionic gonadotropin level. Unfortunately, the patient's clinical condition deteriorated rapidly and he died before receiving any treatment for his cancer. However, chemotherapy may play a useful role in the management of systemic disease in patients with dedifferentiated chordoma.

Full Text

Duke Authors

Cited Authors

  • Munshi, HG; Merajver, SD; Valdez, R; Baker, LH; Cooney, KA

Published Date

  • June 2002

Published In

Volume / Issue

  • 25 / 3

Start / End Page

  • 274 - 276

PubMed ID

  • 12040287

International Standard Serial Number (ISSN)

  • 0277-3732

Digital Object Identifier (DOI)

  • 10.1097/00000421-200206000-00014


  • eng

Conference Location

  • United States