The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block.

Published

Journal Article

Cardiac resynchronization therapy (CRT) has revolutionized the care of patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB); some hypothesize that electrical resynchronization may also benefit patients with heart failure with preserved ejection fraction (HFpEF) and LBBB. We assessed the acute hemodynamic and mechanical impact of temporary LV pacing in 2 patients with HFpEF and LBBB and a "classic" pattern of echocardiographic dyssynchrony. LV pacing facilitated electrical resynchronization with acute resolution of mechanical dyssynchrony and improvements in invasively and non-invasively measured global cardiac function, due in part to shortening of the isovolumetric contraction period.

Full Text

Duke Authors

Cited Authors

  • Friedman, DJ; Emerek, K; Søgaard, P; Vejdani-Jahromi, M; Kisslo, J; Atwater, BD

Published Date

  • September 2018

Published In

Volume / Issue

  • 51 / 5

Start / End Page

  • 859 - 862

PubMed ID

  • 30177329

Pubmed Central ID

  • 30177329

Electronic International Standard Serial Number (EISSN)

  • 1532-8430

Digital Object Identifier (DOI)

  • 10.1016/j.jelectrocard.2018.07.004

Language

  • eng

Conference Location

  • United States