Monitoring apoptosis and anticancer drug activity in single cells using nanosensors

Book Section

One of the key challenges in biology and medicine has been molecular analysis of single living cells aimed at providing an understanding of the underlying complex mechanisms in the basic, structural, and functional unit of life. This is important in understanding the normal development of cells, how cells respond to external stimuli, and how cells progress from normal to pathological states. About a decade ago, we envisioned and expressed that the application of nanotechnology to molecular and cell biology and medicine would revolutionize the way in which we study cells, signaling networks, and physiological processes, as well as diseases such as cancer.

Full Text

Duke Authors

Cited Authors

  • Kasili, PM; Vo-Dinh, T

Published Date

  • January 1, 2017

Book Title

  • Nanotechnology in Biology and Medicine: Methods, Devices, and Applications, Second Edition

Start / End Page

  • 423 - 438

International Standard Book Number 13 (ISBN-13)

  • 9781439893784

Digital Object Identifier (DOI)

  • 10.4324/9781315374581

Citation Source

  • Scopus